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A Guide To NRG1 Gene Fusion Cancer Clinical Trials

Searching for NRG1 fusion-positive cancer clinical trials can be difficult and understanding all treatment options is overwhelming. Patients with NRG1 fusion-positive cancer may be wondering what the right course of action is to decide which treatment option and clinical trial is right for them.

It doesn’t have to be done alone.

We've created an actionable guide that lays out the considerations when dealing with cancer treatment and clinical trials to ensure no step is missed and to help manage the process.

Steps Step 1

Understanding NRG1 Gene Fusion

Neuregulin 1 (NRG1) gene fusions in tumors are often oncogenic drivers, causing the cancer to grow and spread more quickly than cancers without a mutation. NRG1 is a gene of the epidermal growth factor family and is involved in the proliferation and survival of cells.

Common types of NRG1 gene fusions are:

  • Pancreatic cancer
  • NRG1 Fusion Breast Cancer
  • NRG1 Lung Cancer
  • Prostate cancer
  • Esophageal cancer
  • Colorectal cancer
  • Any locally advanced or metastatic solid tumor with NRG1 gene fusions
  • NRG4
Steps Step 2

How Clinical
Trials Can Help

There are 9 active clinical trials involving NRG1 gene alterations for many different cancer types taking place in the United States. Participating in a clinical trial not only progresses much-needed research, but also gives patients access to these new innovative therapies years before the general population.

The new treatments investigated in today’s cancer clinical trials are:

  • Targeted therapies for new biomarkers
  • Immunotherapy using new monoclonal antibodies
  • Combinations of chemotherapies with other drugs
  • New methods of surgery
Steps Step 3

How We
Can Help

At Massive Bio, our mission is to enable cancer patients to have equal access to cutting-edge therapies and clinical trials, regardless of their location and/or financial stability.

Our Artificial Intelligence (AI) powered Clinical Trial Matching System connects patients and their treating oncologists to clinical trials according to their unique cancer case.

We enlist dedicated staff to collect medical records and treatment history and match patients to eligible trials near their home. We provide full support throughout your enrollment process to ensure logistics are handled so you can concentrate on your health.

Selin Kurnaz, Co-Founder, CEO

Hear from our
Co-founder & CEO

Selin Kurnaz on how she struggled to find the right treatment for her uncle and started Massive Bio to help others.

There is a major gap between what pharmaceutical companies are working on right now vs. what cancer patients are getting. Massive Bio is revolutionizing this process.

Selin Kurnaz

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